HSPA9 overexpression inhibits apoptin-induced apoptosis in the HepG2 cell line

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HSPA9 overexpression inhibits apoptin-induced apoptosis in the HepG2 cell line.

Apoptin, a small protein derived from chicken anemia virus, possesses the capacity to specifically kill tumor cells while leaving normal cells intact. Previous studies have indicated that the subcellular localization of apoptin appears to be crucial for this tumor-selective activity. Apoptin resides in the cytoplasm of normal cells; however, in cancer cells it translocates into the nucleus. In ...

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ژورنال

عنوان ژورنال: Oncology Reports

سال: 2013

ISSN: 1021-335X,1791-2431

DOI: 10.3892/or.2013.2399